Exceptional Antibodies Produced by Successive Immunizations
نویسندگان
چکیده
منابع مشابه
Exceptional Antibodies Produced by Successive Immunizations
Antibodies stand between us and pathogens. Viruses mutate quickly to avoid detection, and antibodies mutate at similar rates to hunt them down. This death spiral is fueled by specialized proteins and error-prone polymerases that change DNA sequences. Here, we explore how B lymphocytes stay in the race by expressing activation-induced deaminase, which unleashes a tsunami of mutations in the immu...
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ژورنال
عنوان ژورنال: PLOS Biology
سال: 2015
ISSN: 1545-7885
DOI: 10.1371/journal.pbio.1002321